An efficient synthesis of 3-substituted indole derivates under ultrasound irradiation

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An efficient synthesis of 3-substituted indole derivates under ultrasound irradiation.

A solvent-free procedure for the synthesis of 3-substituted indole derivates from indoles and nitroalkenes under ultrasound irradiation is described. Control experiments disclosed besides mechanical effects, namely agitation, sonochemical effects are the main forces to drive the reaction. In the method, 2-chloroethanol was used to prepare a wide variety of 3-substituted indole derivates. This p...

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A Clean and Highly Efficient Synthesis of Oxindole Substituted Pyrrolo[2,3-d]Pyrimidines under Ultrasound Irradiation

A practical and new method for the synthesis oxindole substituted pyrrolo[2,3-d]pyrimidines by the condensation of isatin, acetophenone and 6-amino-uracil under ultrasound irradiation conditions at 60 °C was described. The reaction was developed via a sequential tandem process to afford the oxindole substituted pyrrolo[2,3-d]pyrimidines in good to excellent yields. All reactions performed effic...

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a clean and highly efficient synthesis of oxindole substituted pyrrolo[2,3-d]pyrimidines under ultrasound irradiation

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ژورنال

عنوان ژورنال: Ultrasonics Sonochemistry

سال: 2011

ISSN: 1350-4177

DOI: 10.1016/j.ultsonch.2010.09.007